DESIGNATION: Required
DESCRIPTION: Physical and chemical properties of materials commonly used in medicine. Inflammatory, immunogenic, carcinogenic and toxicologic responses within host tissues. Testing and evaluation strategies for effective use of materials in medicine and biology.
PREREQUISITE: PHYS 2130; MATH 1860 or 1930; CHEM 1240. Co-requisite: BIOL 2150
TEXTBOOK: There is no suggested textbook for Biomaterials. Lecture notes are available on the web in Adobe Acrobat and PowerPoint formats
OBJECTIVES: To apply knowledge of material science to biological systems
The ability to select and design biomaterials for applications as devices in medical and clinical fields
To understand and solve problems arising from material and host tissue interaction following implantation.
To understand regulations on the use of implantable biomaterials (outcome n)
To develop communication skills with papers and presentations
TOPICS COVERED: Biomaterials Science and Engineering Overview
Structure of Solids
Characterization of Materials
Metals
Ceramics/Polymers
Polymers/Hydrogels
Natural Materials
Structure Property Relationships
Tissue Response to Implants
In-vivo and in-vitro testing of biomaterials
Regulatory Environment
Artificial Organs
Cardiovascular Applications
Orthopaedic Applications
SCHEDULE: 2 - 1 hour 15 minute lectures per week
CONTRIBUTION: Engineering Topics
OUTCOMES: This course will develop the following skills that are required of bioengineering graduates:
(b) An ability to design and conduct experiments, as well as to analyze and interpret data
(c) An ability to design a system, component, or process to meet desired needs within realistic constraints such as economic, environmental, social, political, ethical, health and safety, manufacturability, and sustainability
(d) An ability to function on multi-disciplinary teams
(g) An ability to communicate effectively
(h) The broad education necessary to understand the impact of engineering solutions in a global, economic, environmental, and societal context
(i) A recognition of the need for, and an ability to engage in life-long learning
(j) A knowledge of contemporary issues
(8b) The capability to apply advanced mathematics (including differential equations and statistics), science, and engineering to solve the problems at the interface of engineering and biology
PREPARED BY: Scott Molitor (smolitor@eng.utoledo.edu) and Tamara Phares (tphares@eng.utoledo.edu)