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Academic Year 2005-2006

The Board of Governors of the American Institute of Ultrasound in Medicine has elected Dr. Jian-Yu Lu, professor of bioengineering, to the prestigious rank of Fellow for his contributions to the advancement of the field of ultrasound in medicine.

The Departments of Bioengineering (University of Toledo - UT) and Orthopedics (Medical University of Ohio - MUO) in partnership with CAMP Inc., a professional services organization, and industrial collaborators; Valtronic USA, Inc., Enhanced Systems Technologies, Inc., Essential Research, Inc, and FlashPoint Marketing & Communications, Inc., have been awarded a $866,606 grant from the State of Ohio under its Third Frontier initiative. The proposal is entitled "Northern Ohio Center of Excellence in Product Development" and the funding is for 2 years beginning in April 2005. The investigators from UT and MUO are: Drs. Brent D. Cameron (UT), Vijay K. Goel(UT), Scott Molitor(UT), Patricia Relue(UT), and Ashok Biyani(MUO). Under the proposal, this group will aid in the development of a new platform technology in the area of photo-biotherapy for wound healing, a promising application at the intersection of the biosciences, medical, and electronics industries, as well as, perform the clinical testing to evaluate the efficacy of the device in enhancing wound healing.

Dr. Ozan Akkus was named a recipient of the NSF Faculty Early Career Development (CAREER) award for his research on “Development of an Integrated Research and Education Program in Nanobiomechanical Analysis of Skeletal Fragility.” The CAREER award is NSF’s most prestigious commendation for new faculty members and recognizes the early career development activities of scholars most likely to become the academic leaders of the 21st century. CAREER awardees are chosen on the basis of creative, career-development plans that integrate research and education. The CAREER award carries with it a $400,000 stipend towards carrying out the research and educational plan of the scholar.

The Young Investigator Travel Award has been awarded to Dr. Ozan Akkus by NIAMS-ASBMR Scientific Meeting, Bone Quality: What Is It and Can We Measure It? This is a two-day scientific meeting convened by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and American Society for Bone and Mineral Research (ASBMR). Information about the meeting can be accessed through the ASBMR-NIAMS website at www.asbmr.org/bonequality.cfm

Drs. Goel and Akkus have a total of 10 conference presenatations at the Annual Meeting of the Orthopaedic Research Society in Washington DC. ORS information can be accessed through their website at www.ors.org/Ors.asp

In collaboration with Prof. Tarun Goswami, Ohio Northern University, Dr. Vijay Goel has initiated a research project dealing with the long term wear prediction of the artificial spine discs. The project is funded by DePuy Spine, Inc. Raynham, MA.

Professor Goel is the Co-editor of the special issue Roundtables in Spine Surgery; Spine Biomechanics: Evaluation of Motion Preservation Devices and Relevant Terminology, Goel VK, Panjabi MM (Eds), Vol 1, Issue 1, St. Louis; Quality Medical Publishing, 2005

Professor Goel is the Chair of the 2006 Summer ASME-BED conference. ASME can be accessed through the following website www.divisions.asme.org/bed/

Dr. Scott Molitor received a $15,000 grant from the National Organization for Hearing Research. The focus of this grant is to setup hybrid neuron - computer systems to investigate behavior of neurons in the auditory system. This will allow utilizing computer simulations to reproduce some aspect of neuron behavior. These simulations can then be incorporated into recordings from neurons in real-time to test hypotheses about the mechanisms underlying neuron behavior.

A collaborative effort between The University of Toledo, the Medical College of Ohio (MCO) and the Tokushima University of Japan was awarded the Special Emphasis Best Poster Award at the 31st Annual Meeting of the International Society for the Study of Lumbar Spine, Porto, Portugal, May 31 - June 5, 2004. The poster, titled “Biomechanical basis for using signal changes of pedicle on MRI as an indicator for early diagnosis of spondylolysis”, was authored by Dr. Koichi Sairyo, a visiting professor from Japan. Co-authors include Vijay Goel and Sasidhar Vadapalli (The University of Toledo), and Nabil Ebraheim and Ashok Biyani (Orthopedics, MCO).You can view the winning poster by clicking Biomechanical basis for using signal changes of pedicle on MRI as an indicator for early diagnosis of spondylolysis"

Bioengineering faculty members, Dr. Vijay Goel, Dr. Brent Cameron and Dr. Vik Kapoor have been awarded funding from the Ohio Technology Action Board for their work with Theken Surgical LLC, the University of Akron and the Akron Polymer Laboratory in the development of spinal discs. Congratulations to Drs. Goel, Cameron and Kapoor at the University of Toledo and their collaborators, Theken Surgical, the University of Akron and the Akron Polymer Lab! Click for the article which appeared in the February 27, 2003 Toledo Blade.

Dr. Scott Molitor, Assistant Professor of Bioengineering was recently awarded a 3 year, $213,000 grant from the National Institute of Deafness and Communicative Disorders entitled "Electrophysiologic properties of DCN cartwheel cells". Dr. Molitor’s work will focus on the unique properties of cartwheel cells (CWCs) within the superficial dorsal cochlear nucleus (DCN) that respond to non-auditory signals and inhibit the auditory responses of DCN pyramidal cells.

Professor Vijay K. Goel has been selected to receive the 2003 H. R. Lissner Medal "for significant contributions to the mission of the ASME (American Society of Mechanical Engineers) Bioengineering Division and the growth of the industry, and for his internationally renowned work on spinal implants using finite element modeling and innovative experimental techniques.

The Bioengineering Department has recently established a collaboration with the Tokyo Denki University in Japan. Tokyo Denki is one of the best private technical institutions in Japan. Under the agreement, we hope to exchange students, staff and faculty. In addition, it is our hope that undergraduate students will benefit from this collaborative agreement.

Pfizer Pharmaceuticals, a highly valued member of our Industrial Advisory Committee, has entered into an agreement with the Department of Bioengineering which will allow the incorporation of a Pfizer protocol for the production of Green Fluorescent Protein (GFP) into the Bioprocessing Laboratory for undergraduates. Currently, the Bioprocessing lab guides students through the standard pharmaceutical development of a recombinant organism utilizing beta-Galactosidase as the product. The Pfizer protocol will employ similar molecular biology and analytical chemistry techniques but will result in the production of a protein that is immediately commercially useful. Future students will benefit from the incorporation of up-to-date protocols, techniques and equipment.

In conjunction with the use of the Pfizer protocol for GFP production, Pfizer has also generously offered donations of used equipment from their Discovery Technology labs in Kalamazoo, Michigan. Donations of equipment that are heavily used in the Bioprocessing Lab include items such as Fraction Collectors, Analytical Balances, Centrifuges and Freezers. You can view some pictures of the new equipment here: "Refrigerated Floor Centrifuge""Capillary Electrophoresis""Microbalance"

Dr. Brent Cameron and Dr. Vijay Goel were awarded $47,730 from the AO Foundation in Switzerland for their project titled "Development of a 'Smart' Spinal Disc Implant".